Development methods labeled technetium-99m magnetically nanocolloids for medical diagnosis

Abstract

The opportunity of drawing of a radioactive label 99mTc on a surface nanoparticles of iron Fe2C, covered by a carbon environment, and also particles Fe2C (IDA), modified arenediazoniumtosylates is investigated. It is shown, that on not modified particles about 11,2 % 99mɌɫ from its entered quantity are adsorbed. Thus the size of atomic adsorption does not exceed 0,736·10-9 g-ɚt/g 99mɌɫ on 1 g Fe2C. On the modified particles Fe@C (IDA) physical adsorption is not observed. At their chemical interaction with 99mTc at presence of reducing agent of tin (II) output labeled a product increases more than in 1,5 times and makes 21,3 % from the general entered activity radionuclide. For achievement of higher output carrying out of the researches connected with selection of optimum concentration and conditions of preparation of a reducer or selection of other more effective reducer is necessary. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/20657